SCHEMBL10826432

SCHEMBL10826432

[O-][S+](c1ccc(C=CC(F)(F)F)cc1)c1ccc(C=CC(F)(F)F)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.32
NFE2L2 Q16236 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16651 0.71 CYP2C19 (0.42) NFE2L2
SCHEMBL9227488 0.71 NFE2L2 (0.60) FBP1NFE2L2
SCHEMBL31510225 0.71 APP (0.52) NFE2L2
SCHEMBL31510224 0.71 APP (0.52) NFE2L2
SCHEMBL9227484 0.71 NFE2L2 (0.60) FBP1NFE2L2
SCHEMBL9227835 0.71 AHR (0.48) FBP1NFE2L2
SCHEMBL2875295 0.70 NFE2L2 (0.54) FBP1NFE2L2
SCHEMBL9800772 0.70 NFE2L2 (0.54) FBP1NFE2L2
SCHEMBL115403 0.70 NFE2L2 (0.54) FBP1NFE2L2
SCHEMBL7873732 0.69 NFE2L2 (0.52) FBP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61205252-A None JP disclosed
JP-61205251-A None JP disclosed
JP-S61205252-A FLUROINE-CONTAINING SULFOXIDE DAIKIN IND LTD 1986-09-11 JP disclosed
JP-S61205251-A FLUORINE-CONTAINING SULFOXIDE DAIKIN IND LTD 1986-09-11 JP disclosed