Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622495 | 0.84 | PTGS1 (0.67) | PTGS2KDM4EMAPTL3MBTL1PTGS1 | |
| SCHEMBL8054469 | 0.83 | ACE2 (0.50) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL12869644 | 0.83 | CA1 (0.56) | KDM4EGAACA12CA1CA2 | |
| SCHEMBL7995066 | 0.81 | ELANE (0.37) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL383610 | 0.80 | HSP90AA1 (0.60) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL9068206 | 0.79 | KDM4E (0.55) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL9635367 | 0.79 | ACE2 (0.42) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL10828169 | 0.78 | ELANE (0.60) | PTGS2KDM4EGAACA12CA1 | |
| SCHEMBL9636818 | 0.77 | TSHR (0.48) | CA12CA1CA2MAPTCA4 | |
| SCHEMBL11667767 | 0.77 | GABRA1 (0.41) | PTGS2KDM4EGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626584-A | Crosslinkable thermotropic polyesters derived from allylically substituted hydroxybenzoic acid and a process for preparing a shaped article of the polyesters | CELANESE CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |