Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636806 | 0.88 | RXRA (0.46) | ELANEKDM4ERXRA | |
| SCHEMBL8080620 | 0.81 | ACE2 (0.56) | ACE2GRM1KMT2AMEN1CYP1A2 | |
| SCHEMBL27825583 | 0.80 | ACE2 (0.46) | ACE2GRM1KMT2AMEN1CYP1A2 | |
| SCHEMBL29171910 | 0.80 | ACE2 (0.46) | ACE2GRM1KMT2AMEN1CYP1A2 | |
| SCHEMBL30848060 | 0.80 | ACE2 (0.46) | ACE2GRM1KMT2AMEN1CYP1A2 | |
| SCHEMBL16742107 | 0.79 | TTR (0.55) | ELANETDP1TTRTHRATHRB | |
| SCHEMBL8054469 | 0.79 | ACE2 (0.50) | ACE2ELANEGRM1KMT2AMEN1 | |
| SCHEMBL10828136 | 0.79 | PTGS2 (0.48) | ACE2ELANEGRM1KMT2AMEN1 | |
| SCHEMBL31733483 | 0.78 | GRM1 (0.51) | ACE2GRM1KMT2AMEN1CYP1A2 | |
| SCHEMBL2438341 | 0.78 | GRM1 (0.51) | ACE2GRM1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283326-B1 | LIQUID CRYSTAL COMPOUNDS WITH 4-(OPTICALLY ACTIVE ALKYL)-3-CYANOPHENYL GROUPS | Chisso Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-4913838-A | LARGE SPONTANEOUS POLARIZATION VALUE | CHISSO CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |