Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.61 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096689 | 0.88 | ANPEP (0.53) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9753175 | 0.83 | TSHR (0.58) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28914347 | 0.81 | PTGS1 (0.58) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2861854 | 0.80 | MAPT (0.66) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10976601 | 0.80 | PTGS1 (0.38) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15264145 | 0.79 | MAPT (0.64) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5662535 | 0.78 | LOXL2 (0.46) | MAPTPTGS1PTGS2ALDH1A1CYP3A4 | |
| SCHEMBL31150150 | 0.77 | PTGS1 (0.72) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4669024 | 0.77 | PTGS1 (0.72) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11306147 | 0.77 | MAPT (0.67) | MAPTPTGS1PTGS2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4504491-A | INSECTICIDE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-03-12 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |