Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485077 | 0.88 | SMN1; SMN2 (0.58) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10548829 | 0.84 | TSHR (0.64) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10828243 | 0.83 | MAPT (0.61) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 | |
| SCHEMBL19716459 | 0.82 | TRPA1 (0.56) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 | |
| SCHEMBL687542 | 0.82 | MAPT (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 | |
| SCHEMBL2861854 | 0.80 | MAPT (0.66) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 | |
| Benzoic Acid SCHEMBL16058242 | 0.80 | TSHR (0.76) | TSHRALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL10985532 | 0.80 | TSHR (0.58) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL15264145 | 0.79 | MAPT (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 | |
| SCHEMBL11214016 | 0.78 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007380-A1 | ARTHROPODICIDES | DUNLENA PTY. LTD. (AU) | 1991-05-30 | — | — | WO | disclosed |
| US-4833163-A | INSECTICIDES, NEMATOCIDES, MITICIDES | ROUSSEL UCLAF (FR) | 1989-05-23 | — | — | US | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |