SCHEMBL1082877

SCHEMBL1082877

C=CC(O)C(N)(C=C)C(O)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1359275 0.75
SCHEMBL3519315 0.75
SCHEMBL3264456 0.71
SCHEMBL11492291 0.67 FDPS (0.33)
SCHEMBL17956895 0.67
SCHEMBL1081465 0.67
SCHEMBL132526 0.65
SCHEMBL2363677 0.64
SCHEMBL7043227 0.63
SCHEMBL4540627 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2464424-B1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER OREAL (FR) 2019-09-25 EP claimed
EP-2651516-B1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'ORÉAL (FR) 2017-06-14 EP claimed
EP-2155153-B1 DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT L'ORÉAL (FR) 2017-03-01 EP claimed
EP-2651935-B1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER ORÉAL L (FR) 2016-11-23 EP claimed
US-9370477-B2 Dyeing composition comprising a fatty substance, a pyrazolopyridine oxidation base and a coupler L'OREAL (FR) 2016-06-21 US claimed
US-9125834-B2 Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler L'OREAL (FR) 2015-09-08 US claimed
EP-2872519-A1 NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS UNIVERSITE DE BORDEAUX (FR) 2015-05-20 EP claimed
US-20140259454-A1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2014-09-18 US claimed
WO-2014009169-A1 NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS UNIVERSITE DE BORDEAUX 1 (FR) 2014-01-16 WO claimed
US-20130312203-A1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER L'OREAL (FR) 2013-11-28 US claimed
US-7578856-B2 Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof L'OREAL S.A. (FR) 2009-08-25 US claimed
US-20080289122-A1 Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof L'OREAL S.A. (FR) 2008-11-27 US claimed
US-20080289121-A1 Method of coloring keratinous fibers comprising application of at least one aminopyrazolopyridine oxidation base in the absence of chemical oxidizing agents L'ORE'AL S.A. (FR) 2008-11-27 US claimed
EP-1992331-A1 Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol L'Oreal (FR) 2008-11-19 EP claimed
EP-1992330-A2 Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent L'Oreal (FR) 2008-11-19 EP claimed
EP-1992329-A1 Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer L'Oréal (FR) 2008-11-19 EP claimed
EP-0712923-B1 Lubricants and fluids containing thiocarbamates and phosphorus esters LUBRIZOL CORP (US) 2007-08-29 EP claimed
US-5843873-A Lubricants and fluids containing thiocarbamates and phosphorus THE LUBRIZOL CORPORATION (US) 1998-12-01 US claimed
EP-0869163-A1 Method for reducing engine friction MOBIL OIL CORPORATION (US) 1998-10-07 EP claimed
EP-0712923-A1 Lubricants and fluids containing thiocarbamates and phosphorus esters The Lubrizol Corporation (US) 1996-05-22 EP claimed