Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829944 | 0.81 | MAPK1 (0.42) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL25604502 | 0.74 | ALDH1A1 (0.41) | MAPK1DRD2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL24992266 | 0.72 | KDM4E (0.36) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL30931199 | 0.72 | KDM4E (0.36) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL10829330 | 0.72 | MAPK1 (0.50) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL21585684 | 0.67 | DPP4 (0.39) | DRD2 | |
| SCHEMBL4367785 | 0.67 | PRKAB2 (0.38) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL4363300 | 0.67 | PRKAB2 (0.38) | MAPK1DRD2KDM4EMTNR1AALDH1A1 | |
| SCHEMBL12749270 | 0.66 | MAPK1 (0.33) | MAPK1DRD2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1477813 | 0.66 | MAPK1 (0.33) | MAPK1DRD2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617407-A | ANTIASTHMA, ANTIALLERGEN, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1986-10-14 | — | — | US | disclosed |