SCHEMBL10829329

SCHEMBL10829329

CC(C)(C)OC(=O)N[C@H]([C]=O)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSK P43235 14/20 0.44
CTSS P25774 13/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CYP2D6 P10635 1/20 0.43
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401413 1.00 CTSK (0.44) CTSKCTSSCA1CA2CA7
SCHEMBL8719643 0.86 CYP2D6 (0.54) CTSKCTSSCA1CA2CA7
SCHEMBL3498621 0.86 CYP2D6 (0.54) CTSKCTSSCA1CA2CA7
SCHEMBL26110455 0.85 CTSS (0.50) CTSKCTSSCA1CA2CA7
SCHEMBL26110452 0.85 CTSS (0.50) CTSKCTSSCA1CA2CA7
SCHEMBL6769450 0.85 CTSK (0.43) CTSKCTSSCA1CA2CA7
SCHEMBL6633918 0.85 CTSK (0.43) CTSKCTSSCA1CA2CA7
SCHEMBL16762943 0.85 CTSK (0.43) CTSKCTSSCA1CA2CA7
SCHEMBL27926619 0.85 CTSK (0.43) CTSKCTSSCA1CA2CA7
SCHEMBL2719723 0.85 CTSS (0.50) CTSKCTSSCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109010830-A Application of the blood platelet related inhibitors in preparation treatment decrease of platelet disease drug 苏州大学 2018-12-18 CN claimed
CN-1889974-A Oligopeptides as coating material for medical products HEMOTEQ GMBH (DE) 2007-01-03 CN claimed
CN-109010830-B Application of platelet related inhibitor in preparation of medicine for treating thrombocytopenia 苏州大学 2022-06-07 CN disclosed
CN-109010830-A Application of the blood platelet related inhibitors in preparation treatment decrease of platelet disease drug 苏州大学 2018-12-18 CN disclosed
CN-1889974-B Oligopeptides as coating material for medical products HEMOTEQ GMBH 2012-08-29 CN disclosed
CN-1889974-A Oligopeptides as coating material for medical products HEMOTEQ GMBH (DE) 2007-01-03 CN disclosed
US-4596790-A Pharmaceuticals NYEGAARD & CO. A/S (NO) 1986-06-24 US disclosed
EP-0156063-A2 Hypoglycaemic tetrapeptides Reichelt, Karl Ludvig (NO) 1985-10-02 EP disclosed