Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844679 | 0.83 | LMNA (0.52) | PPARGPPARACYP1A2SCN4ARAB9A | |
| SCHEMBL6844672 | 0.83 | LMNA (0.52) | PPARGPPARACYP1A2SCN4ARAB9A | |
| SCHEMBL1548918 | 0.80 | PPARG (0.59) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL28619870 | 0.79 | PPARA (0.58) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL21895800 | 0.79 | PPARA (0.58) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL25185792 | 0.79 | PPARG (0.58) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL21896404 | 0.79 | PPARG (0.58) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL1305299 | 0.79 | PPARA (0.58) | PPARGPPARACYP1A2MEN1KMT2A | |
| SCHEMBL11071239 | 0.78 | NR4A2 (0.61) | PPARGPPARANR4A2RAB9A | |
| Water SCHEMBL11798405 | 0.77 | PPARA (0.56) | PPARGPPARACYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4632933-A | Sulfur-containing imidazole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-12-30 | — | — | US | disclosed |
| EP-0120239-A2 | Sulfur-containing imidazole derivatives | MERCK PATENT GmbH (DE) | 1984-10-03 | — | — | EP | disclosed |