Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | MAOA | P21397 | 7/20 | 0.70 |
| ▸ | MAOB | P27338 | 7/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196813 | 0.90 | MAOB (0.82) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL30260447 | 0.86 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL10830716 | 0.86 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL25016354 | 0.86 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL4694194 | 0.86 | NFE2L2 (0.69) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL4694196 | 0.86 | NFE2L2 (0.69) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL5437092 | 0.82 | MAOB (0.86) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL25194887 | 0.82 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL30277220 | 0.82 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 | |
| SCHEMBL30383370 | 0.82 | MAPT (1.00) | MAPTKMT2AMAPK1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571409-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-18 | — | — | US | disclosed |
| EP-0075207-B1 | AMINOPROPANOL DERIVATIVES OF 2-HYDROXY-BETA-PHENYL PROPIOPHENONES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1986-02-05 | — | — | EP | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |