SCHEMBL10830352

SCHEMBL10830352

CC(=O)OC1C=CC(=O)C1C(C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALOX5 P09917 1/20 0.32
POLB P06746 2/20 0.32
PPARG P37231 2/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10714369 0.82 FAAH (0.31)
SCHEMBL23593366 0.76 POLB (0.34) CA1CA2ALOX5POLB
SCHEMBL6678682 0.76 POLB (0.40) CA1CA2ALOX5POLBPPARG
SCHEMBL10714782 0.76 POLB (0.34) CA1CA2ALOX5POLB
Methyl Alcohol SCHEMBL6679682 0.74 POLB (0.39) CA1CA2ALOX5POLB
SCHEMBL10830934 0.71 PPARG (0.39) CA1CA2POLBPPARGPPARD
SCHEMBL10711832 0.69 PPARG (0.35) POLBPPARGPPARDPPARA
SCHEMBL10831038 0.69 PPARG (0.46) POLBPPARGPPARDPPARA
SCHEMBL10561513 0.68 PTPN1 (0.30)
SCHEMBL10929223 0.68 SLC18A3 (0.39) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4608442-A TREATMENT OF CORRESPONDING 2-ACYLOXY-4- CYCLOPENTENONES WITH ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-26 US disclosed
EP-0133251-A2 Process for preparing 4-hydroxy-2-cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-02-20 EP disclosed