Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678682 | 0.98 | POLB (0.40) | POLBCA2CA1CA12CA9 | |
| SCHEMBL23593366 | 0.78 | POLB (0.34) | POLBCA2CA1CA12CA9 | |
| SCHEMBL10714782 | 0.78 | POLB (0.34) | POLBCA2CA1CA12CA9 | |
| SCHEMBL6676309 | 0.74 | MIF (0.33) | — | |
| SCHEMBL10830352 | 0.74 | CA1 (0.33) | POLBCA2CA1ALOX5 | |
| SCHEMBL10830934 | 0.74 | PPARG (0.39) | POLBCA2CA1CYP3A4CYP2C19 | |
| SCHEMBL6680654 | 0.74 | ALDH1A1 (0.41) | CYP2C19 | |
| SCHEMBL10831038 | 0.72 | PPARG (0.46) | POLBCYP3A4CYP2C19 | |
| SCHEMBL6679387 | 0.72 | NLRP3 (0.38) | CYP2C19 | |
| SCHEMBL10929223 | 0.70 | SLC18A3 (0.39) | POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |