Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | APC | P25054 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382158 | 1.00 | NOD2 (0.48) | NOD2APCOPRM1OPRD1OPRK1 | |
| SCHEMBL10832327 | 0.88 | NOD2 (0.57) | NOD2OPRM1OPRD1ANPEPESR1 | |
| SCHEMBL10832236 | 0.86 | NOD2 (0.50) | NOD2ANPEPESR1PGRHTR1A | |
| SCHEMBL11113553 | 0.80 | NOD2 (0.49) | NOD2OPRM1OPRD1OPRK1ANPEP | |
| SCHEMBL10831494 | 0.79 | NOD2 (0.44) | NOD2OPRM1OPRD1OPRK1ANPEP | |
| SCHEMBL10832555 | 0.79 | NOD2 (0.42) | NOD2ANPEPLGALS8ESR1PGR | |
| Water SCHEMBL10831450 | 0.79 | NOD2 (0.72) | NOD2OPRM1OPRD1OPRK1ANPEP | |
| SCHEMBL10383211 | 0.78 | NOD2 (0.62) | NOD2OPRM1OPRD1OPRK1ANPEP | |
| SCHEMBL10832586 | 0.77 | NOD2 (0.60) | NOD2ANPEPESR1PGRHTR1A | |
| SCHEMBL11116037 | 0.77 | ESR1 (0.52) | NOD2ANPEPESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4574058-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1986-03-04 | — | — | US | disclosed |
| US-4446128-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |