Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117502 | 0.93 | ANPEP (0.38) | NOD2MCHR1ANPEPRENSSTR1 | |
| SCHEMBL10832236 | 0.92 | NOD2 (0.50) | NOD2MCHR1ANPEPSSTR1SSTR2 | |
| SCHEMBL10832327 | 0.86 | NOD2 (0.57) | NOD2MCHR1ANPEPSSTR1SSTR2 | |
| SCHEMBL10831494 | 0.85 | NOD2 (0.44) | NOD2MCHR1ANPEPSSTR1SSTR2 | |
| SCHEMBL10831595 | 0.83 | L3MBTL1 (0.40) | REN | |
| SCHEMBL14612260 | 0.80 | NOD2 (0.53) | NOD2ANPEPESR1PGRHTR1A | |
| SCHEMBL11116037 | 0.80 | ESR1 (0.52) | NOD2ANPEPESR1PGRHTR1A | |
| SCHEMBL11113553 | 0.79 | NOD2 (0.49) | NOD2ANPEPESR1PGRHTR1A | |
| SCHEMBL10831718 | 0.79 | NOD2 (0.48) | NOD2ANPEPLGALS8ESR1PGR | |
| SCHEMBL10382158 | 0.79 | NOD2 (0.48) | NOD2ANPEPLGALS8ESR1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4574058-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1986-03-04 | — | — | US | disclosed |
| US-4446128-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |
| US-4397844-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1983-08-09 | — | — | US | disclosed |
| EP-0003833-B1 | ANTIGEN DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |