⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721186 | 0.83 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL7264215 | 0.81 | ABCC3 (0.34) | — | |
| SCHEMBL1683508 | 0.79 | LMNA (0.39) | — | |
| Hydrochloric Acid SCHEMBL7170456 | 0.75 | — | — | |
| SCHEMBL11464224 | 0.69 | SLC6A4 (0.36) | — | |
| SCHEMBL3477742 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL22162261 | 0.65 | SIGMAR1 (0.31) | — | |
| Diethanolamine SCHEMBL1836502 | 0.65 | — | — | |
| SCHEMBL1344675 | 0.65 | — | — | |
| Diethanolamine SCHEMBL7037644 | 0.65 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269644-A2 | Microfluidized oil-in-water emulsions and vaccine compositions | Pfizer Products Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1742659-A1 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | Pfizer Products Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| US-7122191-B2 | Microfluidized oil-in-water emulsions and vaccine compositions | PFIZER INC. (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1613346-A2 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | Pfizer Products Inc. (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005097181-A1 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | PFIZER PRODUCTS INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050220814-A1 | Microfluidized oil-in-water emulsions and vaccine compositions | ZOETIS SERVICES LLC | 2005-10-06 | — | — | US | disclosed |
| US-20040258701-A1 | Microfluidized oil-in-water emulsions and vaccine compositions | PFIZER INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004087204-A2 | MICROFLUIDIZED OIL-IN-WATER EMULSIONS AND VACCINE COMPOSITIONS | PFIZER PRODUCTS INC. (US) | 2004-10-14 | — | — | WO | disclosed |