Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22127605 | 0.79 | TSHR (0.37) | L3MBTL1POLBTSHRSMN1; SMN2GLA | |
| SCHEMBL6353034 | 0.77 | MAPT (0.38) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL21854629 | 0.76 | MAPK1 (0.37) | L3MBTL1TSHRSMN1; SMN2GLALMNA | |
| SCHEMBL16931286 | 0.76 | POLB (0.39) | POLBTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL23002174 | 0.75 | CYP2D6 (0.38) | TSHRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL27405623 | 0.74 | MAPT (0.45) | POLBTSHRLMNAALDH1A1KMT2A | |
| SCHEMBL907623 | 0.74 | MAPT (0.45) | POLBTSHRLMNAALDH1A1KMT2A | |
| SCHEMBL7498041 | 0.73 | GLA (0.62) | L3MBTL1POLBTSHRSMN1; SMN2GLA | |
| SCHEMBL643035 | 0.73 | GLA (0.62) | L3MBTL1POLBTSHRSMN1; SMN2GLA | |
| SCHEMBL7306269 | 0.72 | MAPT (0.34) | POLBLMNAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578378-A | (Oxoheterocyclic carbonamido)cephem carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |