Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353034 | 0.81 | MAPT (0.38) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL27677514 | 0.77 | MAPT (0.33) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL23002174 | 0.75 | CYP2D6 (0.38) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL10831751 | 0.72 | L3MBTL1 (0.39) | MAPTGAALMNAKDM4EMEN1 | |
| SCHEMBL4147833 | 0.72 | MAPT (0.33) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL26471684 | 0.72 | ESR2 (0.34) | MAPTGAALMNAKDM4EMEN1 | |
| SCHEMBL23119015 | 0.72 | TSHR (0.60) | MAPT | |
| SCHEMBL4853532 | 0.72 | TSHR (0.60) | MAPT | |
| Hydrochloric Acid SCHEMBL2790413 | 0.71 | TSHR (0.62) | MAPTGAAPKM | |
| Hydrochloric Acid SCHEMBL19953531 | 0.71 | TSHR (0.62) | MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |