⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL28561741 | 0.96 | MGAM (0.36) | — | |
| SCHEMBL11230118 | 0.85 | ALDH1A1 (0.42) | — | |
| SCHEMBL9495243 | 0.82 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL15555876 | 0.81 | ALDH1A1 (0.41) | — | |
| SCHEMBL4958110 | 0.81 | — | — | |
| SCHEMBL7523056 | 0.81 | — | — | |
| SCHEMBL23878228 | 0.79 | ACACB (0.36) | — | |
| SCHEMBL8865650 | 0.79 | ACACB (0.38) | — | |
| SCHEMBL8076302 | 0.79 | CYP2C9 (0.45) | — | |
| SCHEMBL11212585 | 0.79 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968381-A1 | SUGAR-LINKER-DRUG CONJUGATES | Hecht, Sidney (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145109-A1 | SUGAR-LINKER-DRUG CONJUGATES | ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF, ARIZONA STATE UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-0083764-B1 | PROCESS FOR THE PREPARATION OF CARBAMATES | BASF Aktiengesellschaft (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0083764-A2 | Process for the preparation of carbamates | BASF Aktiengesellschaft (DE) | 1983-07-20 | — | — | EP | disclosed |
| US-4331438-A | TREATMENT WITH A FORMALDEHYDE ACCEPTOR | BASF WYANDOTTE CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |