Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493882 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTGAAMGAM | |
| SCHEMBL11141020 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTTGAAMGAM | |
| SCHEMBL8865650 | 0.84 | ACACB (0.38) | SMN1; SMN2LMNAHTTGAAMGAM | |
| SCHEMBL2344865 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHTTGAAMGAM | |
| SCHEMBL9494659 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTMAPK1ALDH1A1 | |
| SCHEMBL11498164 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTGAAMGAM | |
| SCHEMBL10831764 | 0.82 | — | — | |
| SCHEMBL11230118 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2LMNAGAAMGAMSI | |
| SCHEMBL906813 | 0.79 | — | — | |
| SCHEMBL27634047 | 0.79 | LMNA (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179223-A | Reacting primary amine, urea and oxime | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |