Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14662152 | 0.83 | CYP2C19 (0.44) | KDM4ECYP2C19NCF1GAASLC2A1 | |
| SCHEMBL14670113 | 0.83 | CYP2C19 (0.44) | KDM4ECYP2C19NCF1GAASLC2A1 | |
| SCHEMBL2122821 | 0.80 | TSHR (0.58) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL28317278 | 0.79 | NCF1 (0.40) | KDM4EHPGDNCF1GAASLC2A1 | |
| SCHEMBL9025129 | 0.78 | NCF1 (0.42) | KDM4EHPGDNCF1SLC2A1ALDH1A1 | |
| SCHEMBL10831149 | 0.78 | TSHR (0.47) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL10831309 | 0.78 | KDM4E (0.47) | KDM4ETSHRHPGDHSD17B10GAA | |
| SCHEMBL30528606 | 0.77 | TSHR (0.56) | KDM4ETSHRHPGDHSD17B10CYP2C19 | |
| SCHEMBL3568604 | 0.77 | TSHR (0.56) | KDM4ETSHRHPGDHSD17B10CYP2C19 | |
| SCHEMBL20156858 | 0.77 | TSHR (0.58) | KDM4ETSHRHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585869-A | ANTIINFLAMMATORY, ANALGESIC, ANTIULCER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4549023-A | ANTINFLAMMATORY AGENTS, ANALGESICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-10-22 | — | — | US | disclosed |
| US-4474964-A | 3-Aminoindazole derivatives | ASAHI, KASEI, KOGYO, KABUSHIKI, KAISHA (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |