Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.39 |
| ▸ | FADS1 | O60427 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831655 | 0.86 | UTS2R (0.41) | UTS2RADRA2ATRPA1ACHEMAPK10 | |
| SCHEMBL10831659 | 0.84 | UTS2R (0.42) | UTS2RADRA2ATRPA1ACHEMAPK10 | |
| SCHEMBL10369104 | 0.82 | GSK3B (0.39) | MAPK1KDM4E | |
| SCHEMBL10368635 | 0.82 | FADS1 (0.46) | MAPK10MAPK8FADS1 | |
| SCHEMBL10831906 | 0.80 | GAA (0.51) | ADRA2ATRPA1ACHEGAA | |
| SCHEMBL3243994 | 0.77 | UTS2R (0.52) | UTS2RADRA2ATRPA1ACHEMAPK10 | |
| SCHEMBL11087609 | 0.77 | TOP2A (0.52) | ADRA2AMAPK1KDM4EGAA | |
| SCHEMBL10830998 | 0.77 | UTS2R (0.40) | UTS2RADRA2ATRPA1ACHEMAPK10 | |
| SCHEMBL10832205 | 0.76 | MAPK10 (0.47) | UTS2RACHEMAPK10MAPK8 | |
| SCHEMBL3104864 | 0.74 | KDM4E (0.48) | ADRA2ATRPA1ACHEMAPK10MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585869-A | ANTIINFLAMMATORY, ANALGESIC, ANTIULCER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4549023-A | ANTINFLAMMATORY AGENTS, ANALGESICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0049779-B1 | 3-AMINOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4474964-A | 3-Aminoindazole derivatives | ASAHI, KASEI, KOGYO, KABUSHIKI, KAISHA (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |