Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.49 |
| ▸ | ILK | Q13418 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831906 | 0.91 | GAA (0.51) | TOP2ARAD52POLBTERTILK | |
| SCHEMBL10367587 | 0.86 | GAA (0.55) | TOP2APOLBNPC1SLC2A1RAB9A | |
| SCHEMBL10831138 | 0.85 | CDC7 (0.46) | TOP2APOLBSLC2A1ALDH1A1KDM4E | |
| SCHEMBL1662606 | 0.82 | UTS2R (0.56) | ALDH1A1KDM4E | |
| SCHEMBL4995598 | 0.81 | GSK3B (0.53) | TOP2ARAD52POLBKMT2ANPC1 | |
| SCHEMBL3243994 | 0.80 | UTS2R (0.52) | KDM4EADRA2AGAA | |
| SCHEMBL10832017 | 0.77 | UTS2R (0.42) | MAPK1KDM4EADRA2AGAA | |
| SCHEMBL3104864 | 0.76 | KDM4E (0.48) | ALDH1A1ILKKDM4EADRA2AGAA | |
| SCHEMBL13996487 | 0.76 | UTS2R (0.50) | ALDH1A1KDM4EADRA2AGAA | |
| SCHEMBL4782717 | 0.76 | TERT (0.52) | RAD52KMT2AALDH1A1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049779-B1 | 3-AMINOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |