Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | APC | P25054 | 3/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831832 | 0.87 | NOD2 (0.49) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL10831592 | 0.80 | NOD2 (0.42) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL11116037 | 0.78 | ESR1 (0.52) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL10382080 | 0.75 | NOD2 (0.51) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL14410715 | 0.66 | SIRT2 (0.53) | SIRT2SIRT1CTSBCTSLSIRT3 | |
| SCHEMBL14590398 | 0.66 | SIRT2 (0.53) | SIRT2SIRT1CTSBCTSLSIRT3 | |
| SCHEMBL11115958 | 0.66 | NOD2 (0.61) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL30340359 | 0.66 | MAPT (0.60) | SIRT2CTSL | |
| SCHEMBL10832327 | 0.65 | NOD2 (0.57) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL24147045 | 0.65 | CTSL (0.59) | SIRT2SIRT1TPSAB1CTSLSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4574058-A | Antigen derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1986-03-04 | — | — | US | disclosed |