Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | QPCT | Q16769 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832667 | 0.86 | CYP1A2 (1.00) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10831942 | 0.86 | ALDH1A1 (1.00) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10833298 | 0.83 | CYP1A2 (0.93) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1775043 | 0.83 | CYP1A2 (0.79) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10832177 | 0.82 | CYP1A2 (0.91) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10832419 | 0.81 | CYP1A2 (0.77) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10831990 | 0.81 | CYP1A2 (0.77) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10833094 | 0.81 | CYP1A2 (0.77) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10833053 | 0.81 | LMNA (0.76) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL76307 | 0.81 | QPCT (1.00) | ALOX15HSD17B10CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4576957-A | HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1986-03-18 | — | — | US | claimed |