Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199520 | 0.84 | SLC18A3 (0.43) | BCHECHRM4CHRM3KMT2AMEN1 | |
| SCHEMBL19328433 | 0.83 | MEN1 (0.44) | BCHECHRM4CHRM3KMT2AMEN1 | |
| SCHEMBL17785114 | 0.83 | MEN1 (0.44) | BCHECHRM4CHRM3KMT2AMEN1 | |
| SCHEMBL2151170 | 0.81 | MEN1 (0.42) | BCHECHRM4CHRM3KMT2AMEN1 | |
| SCHEMBL29177227 | 0.81 | MEN1 (0.46) | KMT2AMEN1CYP2C19HCRTR2L3MBTL1 | |
| SCHEMBL13278373 | 0.79 | MEN1 (0.41) | BCHEKMT2AMEN1CYP2C19HCRTR2 | |
| SCHEMBL14038138 | 0.79 | MEN1 (0.41) | BCHEKMT2AMEN1CYP2C19HCRTR2 | |
| SCHEMBL12199634 | 0.78 | MEN1 (0.40) | BCHEKMT2AMEN1CYP2C19HCRTR2 | |
| SCHEMBL12199526 | 0.78 | HCRTR2 (0.39) | BCHEKMT2AMEN1CYP2C19HCRTR2 | |
| SCHEMBL12199530 | 0.77 | MEN1 (0.39) | BCHEKMT2AMEN1CYP2C19HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4576933-A | Method of use of 1-(alkyl for alkylcarbanoyl)-2-carbamoylglycerol derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-03-18 | — | — | US | disclosed |