Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785114 | 0.86 | MEN1 (0.44) | KMT2AMEN1CYP2C19BCHETSHR | |
| SCHEMBL19328433 | 0.86 | MEN1 (0.44) | KMT2AMEN1CYP2C19BCHETSHR | |
| SCHEMBL12199639 | 0.84 | SLC18A3 (0.41) | SLC18A3KMT2AMEN1CYP2C19BCHE | |
| SCHEMBL10833008 | 0.84 | BCHE (0.45) | KMT2AMEN1CYP2C19BCHETSHR | |
| SCHEMBL2151170 | 0.83 | MEN1 (0.42) | KMT2AMEN1CYP2C19BCHETSHR | |
| SCHEMBL29177227 | 0.83 | MEN1 (0.46) | KMT2AMEN1CYP2C19TSHRHCRTR2 | |
| SCHEMBL19543487 | 0.82 | GAA (0.38) | SLC18A3KMT2AMEN1CYP2C19BCHE | |
| SCHEMBL13278373 | 0.82 | MEN1 (0.41) | SLC18A3KMT2AMEN1CYP2C19BCHE | |
| SCHEMBL14038138 | 0.82 | MEN1 (0.41) | SLC18A3KMT2AMEN1CYP2C19BCHE | |
| SCHEMBL15542891 | 0.81 | ELANE (0.49) | KMT2AMEN1BCHETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | POLYACTIVA PTY LTD | 2014-05-01 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| US-8535655-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | THE BIONICS INSTITUTE OF AUSTRALIA (AU) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | SLC18A3 4431/4885KMT2A 3711/4885MEN1 1026/4885 |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | SLC18A3 4431/4885KMT2A 3711/4885MEN1 1026/4885 |
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | PTGIS, PTGS2, PTGES | SLC18A3 731/4885KMT2A 3825/4885MEN1 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.