Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786062 | 0.84 | TSHR (0.53) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8335422 | 0.77 | TSHR (0.50) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL28185889 | 0.73 | HTT (0.50) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL5325708 | 0.72 | ALDH1A1 (0.67) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7784198 | 0.71 | ALDH1A1 (0.44) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL616174 | 0.69 | ALDH1A1 (0.57) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1985443 | 0.69 | ALDH1A1 (0.57) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL27498066 | 0.69 | ALDH1A1 (0.57) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7769347 | 0.68 | ALDH1A1 (1.00) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7385780 | 0.68 | ALDH1A1 (0.67) | TSHRALDH1A1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020170-A1 | METAL NANOPARTICLES STABILIZED WITH DERIVATIZED POLYETHYLENEIMINES OR POLYVINYLAMINES | BASF SE (DE) | 2011-01-27 | — | — | US | disclosed |