Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833105 | 0.70 | KCNH2 (0.38) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL23976723 | 0.69 | TLR7 (0.33) | TLR7ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10833652 | 0.65 | TLR7 (0.36) | TLR7TBXAS1ALDH1A1 | |
| SCHEMBL28617610 | 0.65 | ALDH1A1 (0.47) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL28613180 | 0.63 | OPRM1 (0.48) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL31633747 | 0.62 | TLR7 (0.45) | TLR7TBXAS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27839146 | 0.62 | TLR7 (0.45) | TLR7TBXAS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9450646 | 0.62 | GGPS1 (0.45) | TLR7TBXAS1 | |
| SCHEMBL3648059 | 0.62 | TLR7 (0.45) | TLR7TBXAS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31179878 | 0.61 | TLR7 (0.44) | TLR7TBXAS1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593105-A | REACTING ARYLDIAMINE WITH THIOCYANATE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1986-06-03 | — | — | US | disclosed |