Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | BRAF | P15056 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420193 | 0.82 | NPC1 (1.00) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL3473764 | 0.82 | RAB9A (0.70) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL653633 | 0.82 | NPC1 (0.70) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL653441 | 0.81 | RAB9A (0.69) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL29836846 | 0.81 | NPC1 (0.68) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL111544 | 0.80 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL925484 | 0.79 | NPC1 (0.66) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL28838982 | 0.79 | RAB9A (0.66) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL7847490 | 0.78 | NPC1 (0.55) | NPC1RAB9AKMT2ABRAFHDAC1 | |
| SCHEMBL6747205 | 0.78 | NPC1 (0.69) | NPC1RAB9AKMT2ABRAFHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610997-A | Fungicidal N-acylimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-09 | — | — | US | disclosed |
| EP-0141619-A2 | N-Acylimidazoles and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |
| US-4493842-A | Fungicidal N-(phenyl-lower alkanoyl-)-imidazole derivatives, composition, and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0095285-A1 | N-acylimidazoles, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-30 | — | — | EP | disclosed |