Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838982 | 0.90 | RAB9A (0.66) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8736210 | 0.87 | RAB9A (0.62) | RAB9ANPC1KMT2AALDH1A1BRAF | |
| SCHEMBL173275 | 0.83 | NPC1 (0.50) | RAB9ANPC1KMT2ASMN1; SMN2HTT | |
| SCHEMBL27805818 | 0.82 | KMT2A (0.77) | RAB9ANPC1KMT2AALDH1A1BRAF | |
| SCHEMBL31544350 | 0.82 | NPC1 (0.57) | RAB9ANPC1KMT2AALDH1A1BRAF | |
| SCHEMBL1141372 | 0.82 | NPC1 (0.57) | RAB9ANPC1KMT2AALDH1A1BRAF | |
| SCHEMBL3473764 | 0.81 | RAB9A (0.70) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10834286 | 0.81 | NPC1 (0.70) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6420193 | 0.81 | NPC1 (1.00) | RAB9ANPC1KMT2AALDH1A1BRAF | |
| SCHEMBL653633 | 0.81 | NPC1 (0.70) | RAB9ANPC1KMT2AALDH1A1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217552-A | N-phenylcarbazole fluorescent compound for labeling alcohol compounds, and synthetic method and application thereof | 曲阜师范大学 | 2023-06-06 | — | — | CN | claimed |
| US-8586481-B2 | Chemical planarization of copper wafer polishing | APPLIED MATERIALS, INC. (US) | 2013-11-19 | — | — | US | claimed |
| CN-102893376-A | Chemical planarization for copper wafer polishing | APPLIED MATERIALS INC | 2013-01-23 | — | — | CN | claimed |
| US-8119680-B2 | α-Haloketone derivatives of imidazolyl-substituted aromatic compounds and compounds prepared therefrom | NEUROGENETIC PHARMACEUTICALS, INC. (US) | 2012-02-21 | — | — | US | claimed |
| US-20110294293-A1 | CHEMICAL PLANARIZATION OF COPPER WAFER POLISHING | APPLIED MATERIALS, INC. (US) | 2011-12-01 | — | — | US | claimed |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | NEUROGENETIC PHARMACEUTICALS, INC | 2010-12-30 | — | — | US | claimed |
| US-7390429-B2 | Method and composition for electrochemical mechanical polishing processing | APPLIED MATERIALS, INC. (US) | 2008-06-24 | — | — | US | claimed |
| US-20070260058-A1 | Compounds and Uses Thereof in Modulating Amyloid Beta | TORREYPINES THERAPEUTICS INC. | 2007-11-08 | — | — | US | claimed |
| US-20070249833-A1 | such as 2-bromo-1-[6-(4-methyl-imidazole-1-yl)-pyridin-3-yl]-ethanone, which have activity in modulating levels of amyloid-beta, useful in the treatment of neurodegenerative diseases, such as Alzheimer's disease | TORREYPINES THERAPEUTICS INC. | 2007-10-25 | — | — | US | claimed |
| WO-2007047454-A2 | PROCESS AND COMPOSITION FOR ELECTROCHEMICAL MECHANICAL POLISHING | APPLIED MATERIALS, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| EP-0974576-A2 | Method of producing benzamide derivatives | Mitsui Chemicals, Inc. (JP) | 2000-01-26 | — | — | EP | claimed |
| EP-0894512-A1 | Use of stabilised decontaminating compositions for the decontamination of toxic agents and/or pollutants | Irdec S.A. (FR) | 1999-02-03 | — | — | EP | claimed |
| EP-0606762-B1 | Antibacterial resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1998-08-05 | — | — | EP | claimed |
| EP-0390558-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-09-07 | — | — | EP | claimed |
| EP-0606762-A2 | Antibacterial resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-07-20 | — | — | EP | claimed |
| CN-1086812-A | The preparation method of novel aromatization enzyme inhibitor 4 (5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-05-18 | — | — | CN | claimed |
| CN-1046527-A | Novel aromatase inhibitor 4(5) -imidazoles | FARMOS OY (FI) | 1990-10-31 | — | — | CN | claimed |
| EP-0390558-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1990-10-03 | — | — | EP | claimed |
| EP-0007678-B1 | OXIME ETHERS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACF CHEMIEFARMA NV (NL) | 1983-03-30 | — | — | EP | claimed |
| EP-0007678-A1 | Oxime ethers, their preparation and pharmaceutical compositions containing them | ACF CHEMIEFARMA NV (NL) | 1980-02-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260058-A1 | Compounds and Uses Thereof in Modulating Amyloid Beta | APP, BACE1, BACE2 | RAB9A 2158/4885NPC1 61/4885KMT2A 3770/4885 |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | HYPK, APP, NEFM | RAB9A 3673/4885NPC1 229/4885KMT2A 2363/4885 |
| US-20070249833-A1 | such as 2-bromo-1-[6-(4-methyl-imidazole-1-yl)-pyridin-3-yl]-ethanone, which have activity in modulating levels of amyloid-beta, useful in the treatment of neurodegenerative diseases, such as Alzheimer's disease | PSEN2, APP, BACE1 | RAB9A 2805/4885NPC1 719/4885KMT2A 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.