Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835051 | 0.71 | CYP1A2 (0.53) | P2RX7HTTSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL10834837 | 0.71 | CYP1A2 (0.53) | P2RX7HTTSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL9406971 | 0.70 | — | — | |
| SCHEMBL8754765 | 0.68 | CYP1A2 (0.52) | SMN1; SMN2POLBMAPTCYP2D6CYP2C19 | |
| SCHEMBL10625926 | 0.68 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL11071993 | 0.67 | POLQ (0.38) | POLBKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL10481655 | 0.67 | MEN1 (0.35) | SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL24173290 | 0.66 | L3MBTL1 (0.48) | P2RX7HTTSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL30941510 | 0.66 | L3MBTL1 (0.48) | P2RX7HTTSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL441474 | 0.65 | MEN1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567199-A | SOIL INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-28 | — | — | US | disclosed |