SCHEMBL10835148

SCHEMBL10835148

CCOC(=O)CC(C)(C)C(Cl)CC(Cl)(Cl)CC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760131 0.88 MGAM (0.34) HSD11B1MGAMGAASIMGAM2
SCHEMBL10835384 0.87 MGAM (0.33) HSD11B1MGAMGAASIMGAM2
SCHEMBL10456327 0.85 MGAM (0.34) HSD11B1MGAMGAASIMGAM2
SCHEMBL10457808 0.84 KDM4E (0.32) HSD11B1MGAMGAASIMGAM2
SCHEMBL11401898 0.84 MGAM (0.33) HSD11B1MGAMGAASIMGAM2
SCHEMBL10457689 0.83 MGAM (0.32) HSD11B1MGAMGAASIMGAM2
SCHEMBL10456362 0.82 MGAM (0.34) HSD11B1MGAMGAASIMGAM2
SCHEMBL8759600 0.81 GAA (0.38) HSD11B1MGAMGAASIMGAM2
SCHEMBL8159636 0.81 GAA (0.38) HSD11B1MGAMGAASIMGAM2
SCHEMBL11394873 0.75 NAAA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4599358-A Pyrethroids MONTEDISON, S.P.A. (IT) 1986-07-08 US disclosed
EP-0031041-B1 PYRETHROIDS AND THEIR PREPARATION, THEIR PESTICIDAL COMPOSITION; INTERMEDIATES AND THEIR PREPARATION Montedison S.p.A. (IT) 1985-02-13 EP disclosed
EP-0031041-A2 Pyrethroids and their preparation, their pesticidal composition; intermediates and their preparation Montedison S.p.A. (IT) 1981-07-01 EP disclosed