Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693256 | 0.77 | MTOR (0.32) | — | |
| SCHEMBL1072167 | 0.77 | F2 (0.33) | F2LMNAMAPK1HTTCTSK | |
| SCHEMBL20647147 | 0.65 | TSHR (0.44) | LMNAHTTLRRK2 | |
| SCHEMBL15723691 | 0.61 | L3MBTL1 (0.34) | LMNAMAPK1HTT | |
| SCHEMBL5557928 | 0.60 | MAPT (0.31) | — | |
| SCHEMBL20121338 | 0.59 | TOP2A (0.33) | — | |
| SCHEMBL5276629 | 0.58 | MAPT (0.30) | — | |
| SCHEMBL17008796 | 0.58 | HTT (0.38) | F2LMNAMAPK1HTTLRRK2 | |
| SCHEMBL19221422 | 0.58 | F2 (0.34) | F2LMNAMAPK1HTTCTSK | |
| SCHEMBL15652724 | 0.57 | ADORA2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | claimed |
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |