Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835936 | 0.86 | VDR (0.57) | VDRKDM1AMAPTMEN1USP2 | |
| SCHEMBL10835374 | 0.86 | VDR (0.56) | VDRKDM1AMAPTMEN1USP2 | |
| SCHEMBL10835327 | 0.84 | VDR (0.49) | VDRMAPTMEN1USP2ALDH1A1 | |
| SCHEMBL10836141 | 0.83 | VDR (0.50) | VDRKDM1AMAPTMEN1USP2 | |
| SCHEMBL10834734 | 0.83 | VDR (0.59) | VDRKDM1AMAPTTP53 | |
| SCHEMBL10835615 | 0.83 | VDR (0.63) | VDRKDM1AMAPTMEN1USP2 | |
| SCHEMBL11798982 | 0.83 | VDR (0.66) | VDRKDM1AMAPTMEN1USP2 | |
| SCHEMBL10835901 | 0.77 | MAPT (0.61) | VDRMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10835902 | 0.77 | VDR (0.46) | VDRKDM1AMAPTTP53 | |
| SCHEMBL15862031 | 0.75 | VDR (1.00) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618684-A | Substituted indoles | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4485242-A | PRESSURE SENSITIVE CARBONLESS REPRODUCTION | STERLING DRUG INC. (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0035774-A2 | Indoles, process for preparing them and duplicating or marking systems containing them | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | disclosed |