Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 8/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25971947 | 0.84 | TP53 (0.70) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL10835933 | 0.83 | VDR (0.60) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL21399628 | 0.81 | VDR (0.57) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL5936674 | 0.81 | TP53 (0.59) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL8591132 | 0.80 | KDM1A (0.69) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL15862031 | 0.80 | VDR (1.00) | VDR | |
| SCHEMBL21399549 | 0.78 | VDR (0.59) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL3142829 | 0.76 | KIF11 (0.49) | VDRKDM1AMAPTMEN1KMT2A | |
| SCHEMBL19381639 | 0.75 | KDM1A (0.51) | VDRTP53KDM1AMAPTGAA | |
| SCHEMBL5257153 | 0.73 | VDR (0.57) | VDRTP53KDM1AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987037-A | RADIATION-SENSITIVE FREE RADICAL GENERATORS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3954475-A | Photosensitive elements containing chromophore-substituted vinyl-halomethyl-s-triazines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-05-04 | — | — | US | disclosed |