Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751117 | 0.82 | KMT2A (0.43) | CYP2D6CYP2C19KDM4EALDH1A1HDAC6 | |
| SCHEMBL10839348 | 0.78 | CDC7 (0.39) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL2994970 | 0.78 | PARP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL7259310 | 0.77 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10HDAC6 | |
| SCHEMBL1921570 | 0.76 | CYP2D6 (0.62) | CYP2D6CYP2C19KDM4EALDH1A1HDAC6 | |
| SCHEMBL4566107 | 0.74 | HSD17B10 (0.39) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL335962 | 0.73 | MAPT (0.45) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL15059410 | 0.72 | POLB (0.50) | CYP2D6CYP2C19ALDH1A1HSD17B10POLB | |
| SCHEMBL30528370 | 0.72 | POLB (0.50) | CYP2D6CYP2C19ALDH1A1HSD17B10POLB | |
| SCHEMBL29129841 | 0.72 | MAPT (0.46) | KDM4EALDH1A1HPGDHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |