Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259310 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10838759 | 0.80 | HTT (0.46) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL10836335 | 0.78 | CYP2D6 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL335962 | 0.74 | MAPT (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL28773230 | 0.73 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL29129841 | 0.73 | MAPT (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL24620298 | 0.71 | MAPT (0.47) | KDM4EALDH1A1MAPTTSHRSLC6A2 | |
| SCHEMBL7360410 | 0.71 | CHRM5 (0.52) | MAPTSLC6A2KMT2AMEN1LMNA | |
| Salicylamide SCHEMBL28697107 | 0.70 | KDM4E (0.59) | SIRT3TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL14770852 | 0.70 | KMT2A (0.51) | KDM4EALDH1A1HSD17B10MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |