SCHEMBL9558277

SCHEMBL9558277

CC(C)(COCc1ccc(F)c(Oc2ccccc2)c1)c1ccc(OC(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.34
TACR1 P25103 1/20 0.34
TTR P02766 1/20 0.33
LPAR1 Q92633 3/20 0.33
LPAR5 Q9H1C0 3/20 0.33
PPARG P37231 3/20 0.33
PPARA Q07869 3/20 0.33
FFAR4 Q5NUL3 1/20 0.32
CYP2C9 P11712 2/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
PARP1 P09874 1/20 0.32
CSF1R P07333 1/20 0.32
LMNA P02545 1/20 0.32
FFAR1 O14842 2/20 0.32
KCNH2 Q12809 1/20 0.32
CACNA1C Q13936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9838121 0.92 LMNA (0.34) MRGPRX4PPARGPPARACYP2C9POLB
SCHEMBL9798911 0.91 FFAR4 (0.38) TACR1TTRLPAR1LPAR5FFAR4
SCHEMBL10837117 0.91 NPC1 (0.38) TACR1TTRLPAR1LPAR5PPARG
SCHEMBL10836413 0.91 MRGPRX4 (0.33) MRGPRX4TACR1TTRLPAR1LPAR5
SCHEMBL10754114 0.91 MRGPRX4 (0.33) MRGPRX4TACR1TTRLPAR1LPAR5
SCHEMBL10837535 0.90 LPAR1 (0.33) MRGPRX4TACR1TTRLPAR1LPAR5
SCHEMBL10837667 0.89 TACR1 (0.42) TACR1TTRLPAR1LPAR5FFAR4
SCHEMBL10837810 0.89 LTA4H (0.34) TACR1TTRLPAR1LPAR5PPARG
SCHEMBL9558435 0.88 TTR (0.40) TACR1TTRLPAR1LPAR5RAB9A
SCHEMBL10837314 0.88 HTR2A (0.38) TACR1TTRLPAR1LPAR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed