Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836809 | 0.88 | RIPK1 (0.43) | RIPK1SLC6A4HTR2ASLC6A2SLC6A3 | |
| SCHEMBL10548364 | 0.81 | RIPK1 (0.40) | RIPK1SLC6A4HTR2ASLC6A2SLC6A3 | |
| SCHEMBL10853088 | 0.77 | NPC1 (0.41) | TACR1ALDH1A1 | |
| SCHEMBL10548587 | 0.75 | RIPK1 (0.46) | RIPK1SLC6A4HTR2ASLC6A2SLC6A3 | |
| SCHEMBL10856771 | 0.73 | NPC1 (0.42) | TACR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10837314 | 0.72 | HTR2A (0.38) | RIPK1SLC6A4HTR2ATACR1LMNA | |
| SCHEMBL9560406 | 0.72 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10855026 | 0.71 | NPC1 (0.43) | ALDH1A1 | |
| SCHEMBL10837667 | 0.70 | TACR1 (0.42) | RIPK1SLC6A4HTR2ATACR1 | |
| SCHEMBL11334317 | 0.70 | L3MBTL1 (0.42) | SLC6A4HTR2ASCN9ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |