Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837980 | 0.87 | KMT2A (0.47) | RECQLKMT2AMEN1GAANPSR1 | |
| SCHEMBL10838194 | 0.86 | SMO (0.49) | KMT2AMEN1GAANPSR1ALDH1A1 | |
| SCHEMBL10837621 | 0.84 | LMNA (0.60) | RECQLKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL10838059 | 0.83 | LMNA (0.62) | KMT2AMEN1NPSR1ALDH1A1L3MBTL1 | |
| Ofornine SCHEMBL120272 | 0.83 | LMNA (0.62) | KMT2AMEN1NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL10838011 | 0.83 | LMNA (0.62) | KMT2AMEN1NPSR1ALDH1A1L3MBTL1 | |
| Ofornine SCHEMBL30560632 | 0.83 | LMNA (0.62) | KMT2AMEN1NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL10720887 | 0.80 | RECQL (0.63) | RECQLGRM5KMT2AMEN1GAA | |
| SCHEMBL10838784 | 0.80 | NPSR1 (0.50) | KMT2AMEN1GAANPSR1ALDH1A1 | |
| SCHEMBL10838817 | 0.78 | SMN1; SMN2 (0.56) | KMT2AMEN1GAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |