Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.68 |
| ▸ | HTR1A | P08908 | 9/20 | 0.68 |
| ▸ | HTR2A | P28223 | 9/20 | 0.68 |
| ▸ | DRD3 | P35462 | 5/20 | 0.68 |
| ▸ | DRD4 | P21917 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | HTR7 | P34969 | 1/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837085 | 0.89 | DRD2 (0.69) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10838107 | 0.88 | DRD2 (0.68) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10836239 | 0.88 | DRD2 (0.70) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10837661 | 0.85 | DRD2 (0.64) | DRD2HTR1AHTR2ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10836347 | 0.85 | DRD2 (0.67) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10837726 | 0.85 | DRD2 (0.73) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10836552 | 0.84 | DRD2 (0.69) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10835764 | 0.84 | DRD2 (0.68) | DRD2HTR1AHTR2ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10835891 | 0.82 | DRD2 (0.64) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL10838127 | 0.82 | DRD2 (0.68) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |