Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.68 |
| ▸ | DRD3 | P35462 | 8/20 | 0.68 |
| ▸ | DRD4 | P21917 | 7/20 | 0.68 |
| ▸ | HTR1A | P08908 | 8/20 | 0.63 |
| ▸ | HTR2C | P28335 | 4/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836552 | 0.90 | DRD2 (0.69) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL10836239 | 0.88 | DRD2 (0.70) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL11333597 | 0.85 | DRD2 (0.88) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL10837656 | 0.84 | DRD2 (0.68) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL10837085 | 0.83 | DRD2 (0.69) | DRD2DRD3DRD4HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL10835891 | 0.82 | DRD2 (0.64) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL3258405 | 0.82 | DRD2 (0.76) | DRD2DRD3DRD4 | |
| SCHEMBL10838127 | 0.82 | DRD2 (0.68) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL10838107 | 0.82 | DRD2 (0.68) | DRD2DRD3DRD4HTR1AHTR2C | |
| SCHEMBL10864248 | 0.81 | HTR1A (0.63) | DRD2DRD3DRD4HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | claimed |
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |