Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.88 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.88 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.73 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.73 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372183 | 0.93 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL5183040 | 0.92 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10342918 | 0.91 | LTB4R (0.94) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10407813 | 0.89 | LTB4R (0.82) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9821707 | 0.89 | LTB4R (0.79) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9526565 | 0.87 | LTB4R (0.88) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10638812 | 0.87 | LTB4R (0.88) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10632710 | 0.87 | CYSLTR1 (0.95) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL11009012 | 0.87 | LTB4R (0.78) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9201186 | 0.86 | LTB4R (0.74) | LTB4RLTB4R2CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565882-A | Substituted dihydrobenzopyran-2-carboxylates | G. D. SEARLE & CO. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0150447-A2 | Substituted dihydrobenzopyran-2-carboxylates | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |