Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.88 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.88 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.74 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.74 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372183 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9201186 | 0.92 | LTB4R (0.74) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| SCHEMBL10342918 | 0.91 | LTB4R (0.94) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL5694802 | 0.91 | LTB4R (0.90) | LTB4RLTB4R2 | |
| SCHEMBL10632710 | 0.88 | CYSLTR1 (0.95) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10638812 | 0.88 | LTB4R (0.88) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10838232 | 0.87 | LTB4R (0.88) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL5183040 | 0.85 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL9821676 | 0.85 | LTB4R (0.86) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| Sc-41390 SCHEMBL29403478 | 0.85 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527922-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. | SEARLE & CO (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017160-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |