Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840801 | 0.86 | AR (0.47) | ARMAPK1MTNR1ACYP1A2CYP2D6 | |
| SCHEMBL10840727 | 0.78 | AR (0.40) | ARHTR2BBRD4CREBBP | |
| SCHEMBL10841342 | 0.77 | AR (0.43) | ARMTNR1ACRHR1HTR2BADRA2A | |
| SCHEMBL14767430 | 0.71 | AR (0.43) | ARMTNR1AADRA2APNMTADRA2B | |
| SCHEMBL22298131 | 0.71 | AR (0.43) | ARMTNR1AADRA2APNMTADRA2B | |
| SCHEMBL10838799 | 0.70 | AR (0.34) | ARMTNR1AHTR2BBRD4CREBBP | |
| SCHEMBL20870486 | 0.69 | MTNR1A (0.60) | ARMTNR1ABRD4CREBBP | |
| SCHEMBL4139663 | 0.69 | MTNR1A (0.60) | ARMTNR1ABRD4CREBBP | |
| SCHEMBL22262591 | 0.69 | MTNR1A (0.60) | ARMTNR1ABRD4CREBBP | |
| SCHEMBL29659962 | 0.69 | MTNR1A (0.60) | ARMTNR1ABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |