Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 6/20 | 0.31 |
| ▸ | HTR2B | P41595 | 6/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840792 | 0.84 | KDM4E (0.39) | ARMTNR1A | |
| SCHEMBL10841335 | 0.79 | AHR (0.37) | ARHTR2CHTR2BMAPTMTNR1A | |
| SCHEMBL10840724 | 0.79 | BRD4 (0.39) | HTR2CCES1BRD4CREBBPHTR2A | |
| SCHEMBL19511212 | 0.73 | AR (0.35) | ARMTNR1A | |
| SCHEMBL10840649 | 0.72 | AR (0.37) | ARMTNR1A | |
| SCHEMBL10838809 | 0.70 | AR (0.43) | ARBRD4CREBBPHTR2BMTNR1A | |
| SCHEMBL19511225 | 0.67 | AR (0.36) | ARMTNR1A | |
| SCHEMBL9065009 | 0.67 | AR (0.49) | ARHTR2CHTR2AHTR2BMTNR1A | |
| SCHEMBL10841342 | 0.67 | AR (0.43) | ARHTR2CHTR2AHTR2BMTNR1A | |
| SCHEMBL10707953 | 0.66 | HTR2A (0.37) | HTR2CCES1HTR2AHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |