Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111490 | 0.98 | KDM5A (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| SCHEMBL111983 | 0.93 | KDM4E (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| SCHEMBL28283791 | 0.89 | EPHX1 (0.47) | KDM5AKDM4CEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL18331470 | 0.88 | KDM4E (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| SCHEMBL18331526 | 0.88 | KDM4E (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| SCHEMBL18331469 | 0.88 | KDM4E (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| SCHEMBL18331532 | 0.88 | KDM4E (0.41) | KDM5AKDM4CKDM4EMAPK1HIF1A | |
| Bromide SCHEMBL28491945 | 0.87 | EPHX1 (0.46) | KDM5AKDM4CEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL109244 | 0.86 | KDM5A (0.34) | KDM5AKDM4CKDM4EDNM1 | |
| SCHEMBL18331463 | 0.86 | KDM4E (0.42) | KDM5AKDM4CKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |