SCHEMBL111983

SCHEMBL111983

C=C(C)C(=O)NCCCN(C)CC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
KDM5A P29375 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
DNM1 Q05193 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TMEM97 Q5BJF2 4/20 0.35
SIGMAR1 Q99720 4/20 0.35
GAA P10253 1/20 0.34
PAOX Q6QHF9 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111490 0.95 KDM5A (0.41) KDM4EKDM5AKDM4CDNM1TMEM97
SCHEMBL108392 0.93 KDM5A (0.41) KDM4EKDM5AKDM4CDNM1PAOX
SCHEMBL109244 0.89 KDM5A (0.34) KDM4EKDM5AKDM4CDNM1ALDH1A1
SCHEMBL18331463 0.89 KDM4E (0.42) KDM4EKDM5AKDM4CDNM1TMEM97
SCHEMBL18331598 0.89 KDM4E (0.42) KDM4EDNM1TMEM97SIGMAR1PAOX
SCHEMBL18331597 0.89 KDM4E (0.42) KDM4EDNM1TMEM97SIGMAR1PAOX
SCHEMBL28004033 0.88 KDM5A (0.41) KDM4EKDM5AKDM4CDNM1TMEM97
SCHEMBL18331469 0.87 KDM4E (0.41) KDM4EKDM5AKDM4CDNM1TMEM97
SCHEMBL18331532 0.87 KDM4E (0.41) KDM4EKDM5AKDM4CDNM1TMEM97
SCHEMBL18331526 0.87 KDM4E (0.41) KDM4EKDM5AKDM4CDNM1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2391339-B1 COLOR-PRESERVING HAIR TREATMENT AGENTS HENKEL AG & CO KGAA (DE) 2017-05-03 EP disclosed
EP-2306967-B1 COLORATION USING CATIONIZABLE POLYMER HENKEL AG & CO KGAA (DE) 2015-07-29 EP disclosed
EP-2424491-A2 FILM FORMER IN HAIR DYES Henkel AG & Co. KGaA (DE) 2012-03-07 EP disclosed
EP-2306967-A1 COLORATION USING CATIONIZABLE POLYMER Henkel AG & Co. KGaA (DE) 2011-04-13 EP disclosed
WO-2010124897-A2 FILM FORMER IN HAIR DYES HENKEL AG & CO. KGAA (DE) 2010-11-04 WO disclosed
WO-2010086432-A2 COLOR-PRESERVING HAIR TREATMENT AGENTS HENKEL AG & CO. KGAA (DE) 2010-08-05 WO disclosed
WO-2010015442-A1 COLORATION USING CATIONIZABLE POLYMER HENKEL AG & CO. KGAA (DE) 2010-02-11 WO disclosed
US-5525692-A SALT FORMING AN ACRYLIC ESTER OR AMIDE WITH CARBONIC ACID, FORMING AN AMINE SALT CARBONATE MONOMER BEFORE HOMO OR CO-POLYMERIZING, THEN DECARBOXYLATION KOHJIN CO., LTD. (JP) 1996-06-11 US disclosed
EP-0656372-A1 SLUDGE DEHYDRATING AGENT KOHJIN CO. Ltd. (JP) 1995-06-07 EP disclosed