⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839312 | 1.00 | — | — | |
| SCHEMBL10837419 | 0.83 | — | — | |
| SCHEMBL10837413 | 0.83 | — | — | |
| SCHEMBL10837389 | 0.81 | — | — | |
| SCHEMBL10624018 | 0.79 | — | — | |
| SCHEMBL10680887 | 0.78 | — | — | |
| SCHEMBL10838680 | 0.74 | LMNA (0.48) | — | |
| SCHEMBL10838552 | 0.72 | DHFR (0.49) | — | |
| SCHEMBL24543158 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL27673821 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | disclosed |