Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473419 | 0.79 | ADRA2A (0.32) | LMNACYP1A2ADRA2ACYP2D6DRD1 | |
| SCHEMBL4104811 | 0.79 | ADRA2A (0.32) | LMNACYP1A2ADRA2ACYP2D6DRD1 | |
| SCHEMBL1273846 | 0.79 | ADRA2A (0.32) | LMNACYP1A2ADRA2ACYP2D6DRD1 | |
| SCHEMBL10840617 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL30538679 | 0.77 | LMNA (0.32) | LMNACYP1A2ADRA2ACYP2D6DRD1 | |
| SCHEMBL10779716 | 0.70 | — | — | |
| SCHEMBL8974680 | 0.70 | — | — | |
| SCHEMBL10839641 | 0.70 | — | — | |
| SCHEMBL8686357 | 0.69 | — | — | |
| SCHEMBL11104815 | 0.67 | CTSC (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180500-A1 | Thieno and furo[2,3-c]pyrrole derivatives, process for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1986-05-07 | — | — | EP | disclosed |